uMELT: Streamlined DNA Melting Prediction Now
uMELT is a web-based tool designed to predict DNA melting curves – the temperatures at which DNA strands separate. Accurate DNA melting curve prediction is critical in various healthcare bioinformatics applications, including genetic testing and drug development. This review evaluates uMELT's capabilities and limitations, examining its evolution from a Flash-based application to its current web-based iteration. We critically assess its accuracy, compare it to existing software (where data allows), and discuss the need for further validation before widespread clinical use....